Director of Project Engineering

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

RayzeBio, a Bristol Myers Squibb company, is a dynamic biotechnology company headquartered in San Diego, CA. The company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio is developing innovative drugs against targets of solid tumors. Led by a successful and experienced entrepreneurial team, RayzeBio aims to be the global leader in radiopharmaceuticals.

Summary

The Director of Capital Project Engineering is responsible for the successful management and execution of major capital projects ranging from $10M–$150M, with a focus on building, expanding, or renovating largescale radiopharmaceutical manufacturing sites. This role will lead multi-disciplinary engineering teams with potential to have senior manager and associate director level reports, interface with construction management, and oversee all phases of capital project delivery—including design, procurement, installation, commissioning, cost forecasting and validation of facility and various process technologies. As a people leader, the Director fosters a culture of accountability, collaboration, and professional growth by providing clear direction, mentoring team members, developing future leaders, and promoting cross-functional teamwork. The ideal candidate has proven experience in building and scaling large, complex manufacturing facilities, preferably within the radiopharmaceutical industry, and holds a degree in engineering or a related field.

Key Responsibilities

• Directly manage the planning, execution, and delivery of all phases of capital projects (value: $10M– $150M), ensuring adherence to budget, schedule, quality, and regulatory standards.

• Oversee the design, construction, and commissioning of new or expanded manufacturing facilities, with specific experience in radiopharmaceuticals or related pharmaceutical field. • Directly collaborate closely with project stakeholders, including site leadership, process engineers, vendors, contractors, and regulatory bodies.

• Candidate will lead hiring of a team of engineers, senior engineers, managers, and associate directors to build out an organization that supports a manufacturing site.

• Lead technical review and optimization of radiopharmaceutical production and drug product filling equipment.

• Provide technical leadership on building and site design, utility systems, environmental and regulatory compliance, and automation integration.

• Develop and execute project charters, risk assessments, budgets, resource plans, and timelines.

• Review and approve engineering deliverables, technical documents, specifications, and commissioning/qualification protocols.

• Manage and resolve project deviations, CAPAs, and engineering change controls.

• Ensure continuous improvement of project execution processes to optimize site operations and reliability.

• Support site strategy and contribute to expansion plans in Indianapolis and other global locations as needed.

• Oversee and manage overall timeline and ensure deliverables are met

• Uphold all safety standards and ensure safe handling of radioactive materials and hazardous equipment.

• Establish a team of engineers in support construction, validation and ultimately the transition to daily site Engineering operations.

• Mentor engineering staff and support professional development within the engineering team.

Education and Experience

• Required: Bachelor’s degree in an Engineering discipline (Chemical, Mechanical, Electrical, Industrial, or related).

• Preferred: Advanced degree or PMP certification.

• Experience: At least 10 years in engineering roles with direct responsibility for large-scale capital project management ($10M–$150M), including new site builds or major facility expansions.

• Demonstrated experience in radiopharmaceutical or pharmaceutical field required.

• Experience leading multidisciplinary project teams and managing external contractors.

Skills and Qualifications

• Expertise in pharmaceutical engineering, including cGMP and FDA/USP/OSHA regulatory requirements.

• Proven experience developing and leading engineering teams.

• In-depth knowledge and hands-on experience with radiopharmaceutical production, and related GMP facility site builds is desired.

• Strong background in facility and utility systems, aseptic processing, and fill/finish equipment.

• Advanced proficiency in project management methodologies and tools.

• Familiarity with vendor management, contract negotiation, and cost control processes.

• Excellent written and verbal communication, stakeholder, and team leadership skills.

• Proficient in MS Office Suite, CMMS, and building automation systems.

• Willingness to work in radioactive environments and adhere to all necessary safety precautions.

• Ability to travel and support projects at multiple domestic or international locations.

Physical Demands

• Ability to climb ladders and lift up to 50 lbs.

• Regular interaction within laboratory or construction settings, with PPE required in certain areas.

Work Environment

• Noise levels Moderate.

• Exposure to construction, laboratory, and radiopharmaceutical production environments.

The starting compensation for this job is a range from $190,989 - $231,400, plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

#RayzeBio, GPS_2025, #LI-Onsite

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.