Global Program Lead, Early Development Oncology

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Role Summary:

The Global Program Leader (GPL) serves as the “point of accountability” for one or more assets. The GPL role is accountable for leading the Global Program Team and orchestrating the design and execution of a global integrated program strategy from candidate nomination to proof of concept. The GPL develops, leads, and inspires a high performing matrix “dotted line” team. They are responsible for cross-functional stakeholder relationships and input to ensure end to end understanding of upstream and downstream alignment and business implications for the strategy, and its evolution as emerging data and competitive insights unfold.

Technical/Functional Responsibilities

Develops and manages product strategy andearlydrug development program

• Designs & executes cross-functional global drug development strategy from candidate nomination to proof of concept
• Authors/contributes to the creation of the important documents of Early Development: DCRD (Development Candidate Recommendation Document), Target Product Profile (TPP), protocol, ICF, IB, IND, CTA, clinical and/or preclinical study reports, briefing documents for Regulatory Authorities, understands how access, pricing and reimbursement needs for supporting value proposition will inform trial design
• Leads the team in designing clinical pharmacology, dose escalation, expansion, safety, proof of concept or pivotal study proposals
• Leads team in developing the integrated asset development plan, including the Early Clinical Development Plan (CDP), translational development plan (or biomarker plan), technical development plan and/or regulatory plan and key program decision points
• Builds a development plan that is aligned with a broader strategy (TA/Franchise) and endorsed by governance

Integrates commercialization inputs and deliverables to design the optimal early program strategy

• Understands commercial inputs needed to inform early phase trial design and POC achievement, as well as design of late-stage program
• Facility with integrating market inputs into clinical plans, including trial geographic footprint, TPP, Early Access Review, CI insights
• Demonstrates business acumen and familiarity with commercial deliverables up through registration and beyond
• Contributes to the development of brand hallmarks (e.g., generic name) and understands relationships between brand strategy (e.g., preliminary positioning and differentiation) and clinical trial design
• In partnership with medical, supports development of KOL plans and engagements, and leverages KOL input in context of development programs
• Supports commercial needs and recommendations to guide CMC requirements for commercial product

Clinical Trial Design, Execution, and Interpretation

• Utilizes various resources to design clinical trials that are competitively differentiating (e.g., competitive intelligence knowledge, KOL input)
• Actively participates with Health Authorities in finalizing clinical design and adequate endpoints
• Understands clinical trial operational complexities from study start up through enrollment, quality assurance, and study readout
• Has an active role in analysis and/or interpretation of clinical data and translation into scientific communication strategy, including publications, and commercial strategy
• Designs and implements a clinical development program with a joint team which can include providing development options and assessing value and trade-offs to inform recommendations and decision making
• Understands and reflects the impact of VAP inputs (Early Access Review and DEX recommendations, commercial opportunity assessment, TPP requirements, and value drivers as inputs in clinical trial design

Leadership Responsibilities

• Inclusively Collaborates Across the BMS Matrix with an Enterprise Mindset: Effectively collaborates with matrix functions by building trust and driving toward the collective success of the program
• Demonstrates Enterprise Mindset Problem-Solving and Decision Making:Gathers diverse perspectives assess alternate resolutions and makes thoughtful, informed Enterprise decisions
• Develops and Leads a High Performing Matrix Team: Builds, leads and inspires high performing cross functional matrix team through a unified program strategy on behalf of our patientsHolds Oneself and Others Accountable: Takes initiative to address challenges, removes barriers, holds others accountable for the collective success of the program outcomes and team collaboration
• Demonstrates Character: Leads with the values, self-awareness, and humility, seeks feedback, Includes integrity

Minimum Qualifications

• Advanced degreerequired(MD, PharmD, etc.) must have experience in the drug development process
• Proven demonstrated Leadership capability; previous experience in building and leading a high performing team
• Rigorous scientific training with understanding of the role of basic biology, pharmaceutical optimization, and translational medicine in early development
• Drug development training and knowledge of all functional areas of exploratory development, including chemistry/biochemistry, biology, toxicology, CMC, translational medicine, early clinical development
• Direct experience in a scientific function; worked in at least one functional area of early development
• Current knowledge in relevant therapeutic areas
• Direct experience working with different drug modalities: small molecules, biologics, or cell therapies, drug-diagnostic combinations

Additional requirements

• Extensive working knowledge in the end-to-end drug development process, along with expertise in one or more of the relevant areas (e.g., clinical, regulatory, project planning and management, medical, commercial development)
• Prior experience in building a development plan that was aligned with a broader strategy (TA/Franchise) and endorsed by governanceExperience in building trusting cross-functional stakeholder partnershipsin a matrix organization
• Demonstrated ability to constructively influence peers and senior leaders across the enterprise
• Working knowledge of regulations in the pharmaceutical industry (US and Global preferred)
• Demonstrated ability to effectively collaborateacross geographic and functional boundaries (e.g.early development, R&D, disease strategy teams, marketing, access, etc.) and building strong external relationships
• Ability to navigate through a complex and dynamic healthcare environment
• Track record of successfully executing on large, complex projects, with a preference for successful drug trial oversight and execution
• Abreast of scientific issues as they impact business development and strategic planning
• Success in situations requiring rigorous, analytical problem solving and the ability to determine scientific opportunity and commercial targets
• Broad understanding of domestic and international issues relative to the pharmaceutical industry
• Proven agility in prioritizing and navigating competing demands

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If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

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