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Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.Our Chemical Process Development group is a team of organic chemists, analytical chemists, and chemical engineers working together to design novel syntheses from raw materials to supply new medicines to patients. Our scientists focus on developing safe, economical, sustainable, and robust processes to support clinical trials and the launch of new medicines across various drug modalities including small molecules, peptides, oligonucleotides, and antibody drug conjugates. The work is driven by innovative science,data-driven decision-making, and collaborative teamwork. The scientific knowledge package from the manufacturing process, design parameters, and control strategies enables regulatory filings to bring these novel medicines to patients worldwide.Position Summary: This Analytical Development role will be responsible for developing effective collaborations within Chemical Process Development (CPD) project teams consisting of organic chemists, chemical engineers, and analytical scientists to support an increasingly complex portfolio of small molecules and milla-molecular (ADCs, peptides, oligonucleotides) drug candidates. <ul><li>Accountable for providing fit-for-purpose analytical methods and analyses which provide key insights and process knowledge for scale-up and process optimization studies for projects within the portfolio.</li><li>Accountable for collaborating within project teams to provide innovative analytical approaches to help solve challenging problems encountered to support route selection and process optimization studies conducted by chemists and chemical engineers.&nbsp; </li><li>Accountable for developing and transferring methods to other analytical release functions to support the timely release of clinical API batches. </li><li>Partners with other Analytical Functions within CPD, and across Product Development to evolve, integrate and optimize analytical support to create a world-class analytical function.&nbsp;&nbsp; </li><li>Successful candidates expected to grow and advance to become either analytical leaders or technical leads for projects within the CPD portfolio.</li></ul>Key Responsibilities:<ul><li>Responsible for willingly and enthusiastically working at the bench to solve analytical challenges encountered within pharmaceutical development.&nbsp; Can be relied upon to work independently to develop and validate methods, as well as investigate and apply innovative separation techniques such as 2DLC or CE.&nbsp; Seeks opportunities to publish/present work externally.</li><li>Accountable for identifying opportunities and/or implementing solutions to improve monitoring of continuous manufacturing processes, and increasingly applying automation to improve efficiency, productivity, quality or reduce costs.&nbsp; </li><li>Responsible for actively collaborating with other Key Scientists within the team.&nbsp; Expected to consistently display a can-do attitude and demonstrate the willingness and capability to adapt and grow within a complex and changing environment.&nbsp; </li><li>Responsible for working with leadership to develop self, share best practices, work effectively to solve pharmaceutical development problems, and continuously learn and improve.&nbsp; Expected to demonstrate capability to advance upon the technical ladder or become an effective analytical lead within project teams.&nbsp; &nbsp;&nbsp;</li></ul>Experience &amp; Qualifications: <ul><li>Ph.D. in analytical or organic chemistry with 0-2 years of experience or M.S. in analytical or organic chemistry with 2-4 years of experience, or B.S. in analytical or organic chemistry 5-7 years of experience</li><li>Practical experience directly relevant to the role is critical to success and minimum degree requirements change relative to experience.</li><li>Experience with chromatographic and/or spectroscopic techniques preferred. </li><li>Experience in working across matrixed teams highly desirable.</li><li>Demonstrated commitment to safety.</li><li>Excellent interpersonal, collaborative, team building, and communication skills to ensure effective collaborations within matrix teams. Demonstrated performance against cooperation principles and enterprise mindset.&nbsp;</li></ul>If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Compensation Overview:Princeton - NJ - US: $99,330 - $120,366 &amp;#xa;The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.&nbsp; Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit <a href="https://careers.bms.com/life-at-bms/" target="_blank">https://careers.bms.com/life-at-bms/</a>. Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:&nbsp;<a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Bristol Myers Squibb

Scientist, Analytical Development

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.The Senior Clinical Scientist reports through the Clinical Science function which provides scientific expertise necessary to design and deliver clinical studies and programs.Position Summary / Objective<ul><li>Responsible for implementation, planning, and execution of assigned clinical trial activities. Serves as Clinical Trial Lead for one or more trials</li><li>Successfully leads, plans, and executes trial level activities for multiple trials with minimal to moderate level of supervision</li><li>Provides scientific and clinical leadership to team of supporting Clinical Scientists (matrix leadership)</li><li>Co-Leads study team meetings in partnership with GDO protocol manager; and collaborate with cross functional study team members</li><li>May support clinical development planning (collaboration with Clinical Development Lead/Clinical Trial Physician for provision and analysis of data to support future planning)</li></ul>Position Responsibilities<ul><li>Maintain a thorough understanding of assigned protocols and protocol requirements; educate supporting team members</li><li>Plan and lead the implementation all study startup/conduct/close-out activities as applicable</li><li>Evaluate innovative trial designs (collaboration with Medical Monitor/Clinical Development Lead)</li><li>Protocol and ICF development process with minimal guidance; including writing, reviewing, adjudication/resolution of cross functional comments and ensuring high clinical quality (collaboration with Medical Writing)</li><li>Site-facing activities such as training and serving as primary contact for clinical questions</li><li>Activities related to data generation and validation, including CRF design, clinical data review/query resolution; ensure consistent, quality data review by supporting CS team</li><li>Clinical data trend identification; provide trends and escalate questions to Medical Monitor</li><li>Develop clinical narrative plan; review clinical narratives</li><li>Provision of information required by Protocol Manager for development of trial budget, CRO scope of work, etc.</li><li>Review development of site and CRA training materials and presentation at SIV and Investigator meetings and support on Study committee (e.g., DMC) activities</li><li>Drafting/review and validation of clinical study reports (CSRs) and clinical portions of Regulatory Documents (e.g., IB, DSUR, regulatory responses)</li><li>Collaborate and serve as primary liaison between external partners for scientific advice</li></ul>Degree Requirements<ul><li>Degree in Life Sciences (MD, PhD, Pharm D, MS, RN or other scientific field preferred)</li></ul>Experience Requirements<ul><li>5+ years of experience in clinical science, clinical research, or equivalent</li><li>Proficient knowledge of GCP/ICH, drug development process, study design, statistics, clinical operations</li><li>Proficient knowledge and skills to support program specific data review, trend identification, data interpretation</li><li>Knowledge of the establishment and operation of data monitoring committees, dose review teams, and independent response adjudication committees</li></ul>Key Competency Requirements<ul><li>Excellent verbal, written, communication and interpersonal skills</li><li>Must be able to effectively communicate and collaborate across functions and job levels</li><li>Ability to assimilate technical information quickly</li><li>Routinely takes initiative</li><li>Detail-oriented</li><li>Strong sense of teamwork; ability to lead team activities</li><li>Proficient in Medical Terminology and medical writing skills</li><li>Proficient knowledge of the disease area(s), KOLs, indication(s), compound(s) under study (including MOA, PK/PD, biomarker &amp; safety profile)</li><li>Proficient critical thinking, problem solving, decision making skills</li><li>Understanding of functional and cross-functional relationships</li><li>Commitment to Quality</li><li>Adaptable / Flexible - willing and able to adjust to multiple demands and shifting priorities as well as an ability to meet day-to-day challenges with confidence and professionalism</li><li>Proficient planning/project management skills (ability to develop short to mid-range plans that are realistic and effective in meeting goals)</li><li>Proficient in Microsoft Word, Excel, PowerPoint, Electronic Data Capture (e.g., RAVE), J-Review or similar data reporting tools</li></ul>Travel RequiredDomestic and International travel may be required.If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Compensation Overview:Madison - Giralda - NJ - US: $184,270 - $223,294&amp;#xa;Princeton - NJ - US: $184,270 - $223,294 &amp;#xa;The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.&nbsp; Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit <a href="https://careers.bms.com/life-at-bms/" target="_blank">https://careers.bms.com/life-at-bms/</a>. Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:&nbsp;<a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Senior Clinical Scientist, Oncology

SciTec, Inc. is a dynamic small business with the mission to deliver advanced sensor data processing technologies and scientific instrumentation capabilities in support of National Security and Defense. We support customers throughout the Department of Defense and U.S. Government in building innovative new tools to deliver unique, world-class data exploitation capabilities.SciTec has an immediate opportunity for a talented Scientist to join our team in Princeton, NJ or or Dayton, OH developing next generation sensor data processing and exploitation software for the Missile Defense Agency (MDA). Our ideal candidate will be comfortable working to develop performant and maintainable code as part of a rapid pace, collaborative, small-team environment consisting of Scientists, Engineers, and Developers. The successful candidate will be able to prototype, design, integrate, and test advanced software solutions that enable real-time dynamic processing of remote sensing data.Important Notice: SciTec exclusively works on U.S. government contracts that require U.S. citizenship for all employees. Applicants that do not meet this requirement will not be considered.Responsibilities<ul><li>Researching and/or implementing new data processing algorithms and analysis techniques for remote sensor data exploitation</li><li>Characterizing quality of algorithms and models</li><li>Optimize existing high-throughput algorithms surrounding our image analysis, detection, and tracking efforts</li><li>Software engineering to develop, integrate, and test advanced software solutions that enable real-time dynamic processing of remote sensing data</li><li>Other duties as assigned</li></ul><h4>Requirements</h4><ul><li>A Master's degree or higher in Computer Science, Engineering, Physical Sciences, or Mathematics</li><li>Ability to work in a variety of numerical frameworks whether based on C++, Python or MATLAB</li><li>Experience using Git-based code management and version control tools</li><li>Demonstrated experience working as part of a software team</li><li>The ability to obtain and maintain a SECRET DoD security clearance</li><li>Detail oriented and proficient verbal and written communication skills</li><li>Demonstrated ability for cross-discipline collaboration (SciTec's culture emphasizes learning with staff enthusiastic to teach niche topics during the onboarding process and beyond)</li></ul>Candidates who have any of the following skills will be preferred:<ul><li>A PhD degree in Computer Science, Engineering, Physical Sciences, or Mathematics</li><li>5+ years Industry experience</li><li>Experience working on an Agile team and contributing to shared tools</li><li>Professional experience with software prototyping, development, and integration within government frameworks</li><li>Experience developing software for OPIR, EO/IR, SAR, Spectral, RF, or other remotely sensed data</li><li>Knowledge of DevOps techniques, including continuous integration and containerization</li><li>An active DoD Final SECRET security clearance or higher</li></ul><h4>Benefits</h4>SciTec offers a highly competitive salary and benefits package, including:<ul><li>Employee Stock Ownership Plan (ESOP)</li><li>3% Fully Vested Company 401k Contribution (no employee contribution required)</li><li>100% company paid HSA Medical insurance, with a choice of 2 buy-up options</li><li>80% company paid Dental insurance</li><li>100% company paid Vision insurance</li><li>100% company paid Life insurance</li><li>100% company paid Long-term Disability insurance</li><li>Short-term Disability insurance</li><li>Annual Profit-Sharing Plan</li><li>Discretionary Performance Bonus</li><li>Paid Parental Leave</li><li>Generous Paid Time Off, including Holiday, Vacation, and Sick pay</li><li>Flexible Work hours</li></ul>The pay range for this position is $98,000-$146,000. SciTec considers several factors when extending an offer of employment, including but not limited to the role and associated responsibilities, a candidate's work experience, education/training, and key skills. This is not a guarantee of compensation.SciTec is proud to be an Equal Opportunity employer. Vet/Disabled.

SciTec

Staff / Sr. Staff Scientist

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.Role Description:Bristol Myers Squibb Drug Metabolism and Pharmacokinetics (DMPK) Department seeks a passionate Principal Scientist to provide scientific leadership and mentorship within our Transporter Group. The Transporter Group is a center of excellence serving to understand the roles of transporters in drug ADME, efficacy and toxicity and to de-risk the potential for transporter mediated DDIs. The group supports the BMS portfolio through all stages of discovery and development with stage-appropriate, hypothesis driven, in vitro and in vivo transporter assessments; applying mechanism-based approaches to the quantitative translation of pre-clinical in vitro and in vivo data to clinical findings.Key Responsibilities:<ul><li>Provide scientific oversight and mentorship within the Transporter Group, fostering a mindset of scientific rigor, critical thinking, and creative problem-solving.</li><li>Support program teams by proactively identifying transporter-mediated ADME risks; designing, executing, and interpreting data from critical experiments. Effectively communicate findings to teams, prepare and review regulatory source reports.</li><li>Troubleshoot and optimize in vitro transporter assays and identify and implement novel experimental strategies to enhance clinical translation of pre-clinical data.</li><li>Contribute to the strategic direction of the Transporter Group, expanding our science and staying current with literature. Publish and present at internal and external meetings.</li></ul>Qualifications:<ul><li>Ph.D. in biology, toxicology, pharmacology, or related major, with 4+ years of experience in the ADMET field, or Master’s degree with 6+ years relevant ADMET experience.</li><li>Demonstrated ability to mentor and grow team members.</li><li>In-depth expertise in the field of drug transporters, with understanding of ADMET principles.</li><li>Extensive hands-on experience with in vitro drug transporter assays, proven ability in independent experimental design and analysis, with exceptional critical thinking and problem-solving abilities.</li><li>Excellent written and oral communication skills.</li></ul>The starting compensation for this job is a range from $138,850 - $168,300, plus incentive cash and stock&nbsp;opportunities (based on eligibility).&nbsp;The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual&nbsp;compensation will be decided based on demonstrated experience.&nbsp;Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS&nbsp;Career Site.&nbsp;Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical,&nbsp; pharmacy, dental and vision care. Wellbeing support such as the BMS LivingLife Better program and employee assistance programs (EAP).&nbsp;Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental&nbsp;health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays,&nbsp;Global Shutdown days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick&nbsp;time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like&nbsp;tuition reimbursement and a recognition program.If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:&nbsp;<a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Principal Scientist Transporters

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.Translational Medicine at BMSTranslational Medicine is a department within the Research organization that facilitates the transition of drug candidates from early to late-stage clinical development, their approval and life cycle management. Early-stage translational development activities enable rational determination of dose-schedule and responsive patient populations, based on deep understanding of drug mechanism of action and disease segments. Late-stage translational development activities build upon the early work, additionally exploring mechanisms of resistance, rational drug combinations and product differentiation. The late-stage translational development function is responsible for the development of translational strategies to support the development, and maximize the potential, of BMS’s therapies post-clinical proof-of-concept, including registrations and life-cycle management. Translational disease strategies in solid tumor oncology are derived from long term investments in developing data and deep expertise in disease biology, patient segmentation and therapeutic resistance to inform science driven strategies for the development of the oncology pipeline.SummaryReporting to the Oncology Disease Head (Breast Cancer) in Translational Development, the incumbent will be part of the Translational Development team and will help develop translational disease strategies in Breast cancer (BrCa) across multiple asset programs in early and late stage development for approval or life-cycle management in the BMS pipeline. Key responsibility of this role is to effectively collaborate with a cross functional team of asset scientists with deep disease, drug development and business knowledge to help drive an overall translational strategy, working closely with discovery and early development teams, late clinical development as well as with our team of laboratory scientists.Position Description:<ul><li>Develops and executes translational disease strategy in BrCa with deep disease expertise</li><li>Leads and oversees execution of disease strategy including but not limited to various aspects of patient selection strategies</li><li>Serves as scientific expert in generating novel hypotheses for actionable biology based on novel discoveries integrating disease work with literature and deep expertise in BrCa biology</li><li>Manages cross-functional disease project teams with key interfaces in IT, bioinformatics, data sciences, biostatistics, external collaborators, contractors, other disease strategy leads and asset leads</li><li>Maintains relationship with physician scientists for identifying new opportunities and for gaining disease insights</li><li>Identifies needs, gaps and translational disease questions and applies knowledge across all assets in BMS portfolio in the BrCa area</li><li>Leads small and large collaborations with academia and industry partners to identify biobanks, clinical trials and existing databases to collate multi-parameter genomic, immune and clinical datasets to mine for novel biomarkers of unmet need patients in conjunction with computational biologists, data scientists and statisticians</li><li>Collaborates and guides bioinformatics partners on biological questions to deliver biomarkers and biological understanding from whole transcriptome, whole exome, and/or whole genome data, immune profile and single-cell data to support drug discovery and development in the BrCa space</li><li>Manages relationships with key internal stakeholders including Regulatory, Clinical,&nbsp; Commercial, Medical Affairs &amp; Communications and external collaborators to develop translational analysis plans and timelines, communicate analysis results</li><li>Represents the Solid Tumor Translational Development function at various internal meetings and provide domain knowledge and disease expertise to cross-functional teams</li><li>Directs and supports publications in high quality scientific, technical or medical journals</li></ul>Qualifications:<ul><li>PhD degree in a relevant field (e.g. molecular biology, cancer biology, human genetics, immunology)</li><li>3+ years post-PhD experience, with demonstrated scientific leadership in integrating, analyzing and interpreting multimodal translational data in an academic and/or industry setting</li><li>Strong background in human cancer genetics, tumor biology &amp; immunology, genomics/multi-omics with deep understanding of tumor-intrinsic and tumor-extrinsic mechanisms driving cancer development and therapeutic resistance</li><li>Extensive knowledge of high-content biomarker platforms and good understanding of the current clinical practice in BrCa</li><li>Ability to work in a fast-paced environment with rapidly changing and competing priorities and ambiguity</li><li>Strong team player with the ability to work in cross-functional teams. Excellent communication and collaboration skills</li><li>Prior experience with clinical trials preferred</li><li>Strong track record of high-quality scientific publications in relevant fields</li></ul>LI-#ONSITEIf you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:&nbsp;<a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

5 Natural and Environmental Sciences Jobs in Mercer County