field_remote_option

field_job_employment_type

job_industry

field_job_occupational_field_parents_all

job_organization_name

Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise. We are dedicated to creating a diverse and welcoming environment where everyone can thrive.Why join the Wyss Institute at Harvard University?The Wyss Institute’s mission is to transform healthcare and the environment by emulating the way nature builds. We harness the imagination of academia and the focus of industry to translate ground-breaking technologies into commercial products that solve big problems. We support research that universities, companies, and venture capital firms don’t fund because they view it as too risky.&nbsp; We prefer to use the word “challenging,” and we love challenges. For more information&nbsp;<a href="https://wyss.harvard.edu/technologies/" target="_blank">discover our technologies</a>,&nbsp;<a href="https://wyss.harvard.edu/news/" target="_blank">catch up on our recent news</a>, <a href="https://wyss.harvard.edu/multimedia/" target="_blank">or watch our latest videos</a>. Job Description About You:You have a passion for translational research. You want to be a part of a dynamic team dedicated to creating novel approaches to brain delivery of safer, more effective therapeutics. You enjoy working with diverse groups of people and leveraging your expertise to contribute to innovations that can help improve treatment of brain diseases. You thrive in a fast-paced work environment.&nbsp;About the Role:&nbsp;The Wyss Institute’s Brain Targeting Program (BTP), led by Principle Investigator James Gorman, M.D., Ph.D. and Co-PI Donald Ingber, M.D., Ph.D., is developing brain delivery technologies that enable development of breakthrough brain-targeted therapeutics for diverse brain diseases. Our brain delivery platform enables these therapeutic advances by dramatically improving transport of drugs across the blood-brain barrier (BBB) into the brain. For more information on the BTP please visit: <a href="https://wyss.harvard.edu/collaboration/brain-targeting-program/&nbsp;" target="_blank">https://wyss.harvard.edu/collaboration/brain-targeting-program/&nbsp;</a>We are looking for a talented scientist to contribute to the development and characterization of our novel antibody brain shuttle compounds and to optimize our shuttles for specific payloads in neurodegenerative diseases. Reporting to the Principal Scientist, you will work closely with our team using both in vitro cellular systems and in vivo humanized mouse models. You will determine the biophysical properties and brain PK/PD profiles of our shuttle compounds, and assess therapeutic applications of our shuttles.&nbsp;What you'll do:&nbsp;<ul><li>Support in vitro and in vivo validation of antibody shuttles, using protein and cell binding assays, and in vivo brain and blood pharmacokinetics and pharmacodynamic (PK/PD) studies in mouse models</li><li>Participate in vivo studies, including tail-vein injection, tissue (brain, blood and peripheral tissues) harvesting and lysate preparation.</li><li>Perform ELISAs using various types of samples; analysze and summarize data in a timely fashion.</li><li>Under the direction of the Principal Scientist, conduct biophysical characterization of antibodies, including affinity determination with SPR (Biocore) and stability assessment</li><li>Manage one or more projects to optimize shuttles for specific therapeutic payloads to treat specific neurodegenerative diseases.</li><li>Independently develop, validate, and perform various protocols including confocal microscopy, flow cytometry, cell-based assays, plate-based ELISA assays, and others</li><li>Analyze and interpret experimental data, learn new skills, troubleshoot, and contribute intellectually to projects</li><li>Present data and results at internal and external meetings</li><li>Perform support activities and lab maintenance as assigned, and function in a team-oriented environment with other scientists and staff at the Institute, as well as with external collaborators</li><li>Mentor and train less experienced technicians, academic trainees, and others</li><li>Demonstrate a commitment to teamwork, scientific rigor, and collaboration within and across teams.&nbsp;</li></ul> Qualifications What you'll Need:&nbsp;<ul><li>Bachelor’s degree neuroscience, biology, molecular biology, biochemistry, or related field.</li><li>A minimum of 4 years of experience with cell culture, rodent handling, protein/antibody analytics, and molecular and cellular biology techniques such as ELISA, western blotting, confocal imaging, fluorescence-activated cell sorting (FACS), or related experience. Advanced education may count towards years of experience.</li></ul>Desirable Skills:&nbsp;<ul><li>PhD strongly preferred in neuroscience, biology, molecular biology, biochemistry or related field.</li><li>Industry experience preferred.</li><li>Experience with protein science and analytics, including experience with BLI, SPR, SEC and others.</li><li>Ability to work independently as well as to collaborate with a multidisciplinary, diverse group of scientists and allied personnel.</li></ul> Additional Information <ul><li>Standard Hours/Schedule: 35 hours per week</li><li>Pre-Employment Screening: Identity, Education, Criminal, Occupational Health Screening</li><li>Other Information:&nbsp;Offer contingent on successful completion of pre-placement medical evaluation</li></ul>Why you’ll like working with us:&nbsp;&nbsp;At the Wyss Institute, you’re a member of a supportive, dynamic community that is united by its shared goal of changing the world through groundbreaking technology development and commercialization. We encourage your professional growth and development through mentorship and tuition reimbursement to support continued learning, and more. We also support your physical, financial, and mental well-being through generous time off benefits, gym reimbursements, and other programs offered through Harvard. Our facility is located in a new, state-of-the-art life sciences building in the lively Fenway neighborhood, where you have access to multiple amenities including a roof top terrace with stunning views of Boston and proximity to numerous restaurants and cultural attractions.&nbsp; We value an inclusive and diverse workforce, and believe that our differences enrich the work environment for all.&nbsp;Not ready to apply? <a href="https://bit.ly/3XjOml8" target="_blank">Join our talent community</a> to stay up to date on career information and the latest news from the Wyss Institute.&nbsp;Work Format DetailsThis position is based on-site at a Harvard campus location. Additional details will be discussed during the interview process. Certain visa types may limit work location. Individuals must meet work location sponsorship requirements prior to employment.&nbsp;
Salary Grade and RangesThis position is salary grade level 056. Please visit &nbsp;<a href="https://hr.harvard.edu/salary-ranges" target="_blank">Harvard's Salary Ranges</a>  to view the corresponding salary range and related information.&nbsp;
BenefitsHarvard offers a comprehensive benefits package that is designed to support a healthy work-life balance and your physical, mental and financial wellbeing. Because here, you are what matters. Our benefits include, but are not limited to:&nbsp;<ul><li>Generous paid time off including parental leave&nbsp;</li><li>Medical, dental, and vision health insurance coverage starting on day one&nbsp;</li><li>Retirement plans with university contributions&nbsp;</li><li>Wellbeing and mental health resources&nbsp;</li><li>Support for families and caregivers&nbsp;</li><li>Professional development opportunities including tuition assistance and reimbursement&nbsp;</li><li>Commuter benefits, discounts and campus perks&nbsp;</li></ul>Learn more about these and additional benefits on our <a href="https://hr.harvard.edu/benefits-wellbeing" target="_blank">Benefits &amp; Wellbeing Page</a>.&nbsp;
EEO/Non-Discrimination Commitment StatementHarvard University is committed to <a href="https://hr.harvard.edu/sites/g/files/omnuum6281/files/2025-04/reaffirmation_statement.pdf" target="_blank">equal opportunity</a> and <a href="https://provost.harvard.edu/files/provost/files/non-discrimination_and_anti-bullying_policies.pdf" target="_blank">non-discrimination</a>. We seek talent from all parts of society and the world, and we strive to ensure everyone at Harvard thrives. Our differences help our community advance Harvard’s academic purposes.&nbsp;Harvard has an <a href="https://hr.harvard.edu/sites/g/files/omnuum6281/files/2025-04/reaffirmation_statement.pdf" target="_blank">equal employment opportunity</a> policy that outlines our commitment to&nbsp;prohibiting discrimination on the basis of race, sex, ethnicity, color, national origin, religion, disability, or any other characteristic protected by law or identified in the university’s <a href="https://provost.harvard.edu/files/provost/files/non-discrimination_and_anti-bullying_policies.pdf" target="_blank">non-discrimination policy</a>. Harvard’s <a href="https://hr.harvard.edu/sites/g/files/omnuum6281/files/2025-04/reaffirmation_statement.pdf" target="_blank">equal employment opportunity</a> policy and <a href="https://provost.harvard.edu/files/provost/files/non-discrimination_and_anti-bullying_policies.pdf" target="_blank">non-discrimination policy</a> help all community members participate fully in work and campus life free from harassment and discrimination.&nbsp;

Harvard University FAS Human Resources

Scientist I- Brain Targeting Program

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.Position: Senior Principal Scientist , Immunology In Vivo Pharmacology We are seeking an accomplished and visionary Senior Principal Scientist or Associate Director to lead our Immunology in vivo Pharmacology team and drive the in vivo strategy supporting Immunology programs at all stages, from discovery through development. This leadership role is critical to advancing our portfolio and ensuring robust scientific support for candidate selection, human dose projection, biomarker identification, and life cycle management.Key Responsibilities:<ul><li>Lead and mentor the Immunology in vivo Pharmacology team, providing scientific and strategic direction.</li><li>Identify and implement appropriate PK/PD and disease models to support clinical candidate selection, human dose projection, biomarker identification, and life cycle management.</li><li>Design and oversee in vivo and ex vivo studies to assess target engagement and pharmacodynamic endpoints.</li><li>Contribute to portfolio strategy discussions and foster external collaborations to advance program objectives.</li><li>Communicate scientific findings effectively across multidisciplinary teams and to leadership.</li></ul>Qualifications:<ul><li>PhD in a relevant discipline with a minimum of 10 years of post-PhD experience.</li><li>Extensive industry research experience within the Pharmaceutical/Biotechnology sector is highly desirable.</li><li>Demonstrated experience supporting portfolio strategy discussions and managing external collaborations.</li><li>Deep knowledge of the Immunology/Inflammation therapeutic area, with a strong in vivo background.</li><li>Prior hands-on experience with animal models of autoimmune diseases is highly desirable.</li><li>Comprehensive understanding of PK/PD assessments and proven experience designing ex vivo studies for pharmacodynamic and target engagement endpoints.</li><li>Strong scientific and managerial skills, with a proven track record of leadership, collaboration, and excellent communication.</li><li>Publication record in peer-reviewed journals.</li></ul>If you are a driven scientific leader with a passion for advancing immunology research and a commitment to excellence, we invite you to apply and join our team in making a meaningful impact on patient lives.The starting compensation for this job is a range from $181,930 - $220,500 plus incentive cash and stock opportunities (based on eligibility). The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience. For more on benefits, please visit our BMS Careers site. Eligibility for specific benefits listed in our careers site may vary based on the job and location.Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.&nbsp;&nbsp;If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:&nbsp;<a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Bristol Myers Squibb

Senior Principal Scientist- Immunology In Vivo Pharmacology

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.We are seeking a versatile protein engineer to join our Protein Engineering Group in Cambridge, MA in a lab-facing role. The ideal candidate is a scientific innovator with experience in antibody therapeutic engineering and optimization with a deep understanding of protein structure. The successful candidate will contribute to the strategy of biotherapeutic design and utilize their hands-on experiences to drive the successful implementation of these designs in multidisciplinary project teams. This protein engineer will contribute to the production and characterization of multispecific therapeutics through collaborations with the broader Discovery Biotherapeutic community at BMS. This is an ideal position for a protein engineer who is enthusiastic about developing creative solutions to design and optimize a wide range of protein therapeutic modalities for the treatment of diverse diseases.Basic QualificationsBachelor's Degree with 5+ years of academic / industry experienceOrMaster's Degree with 3+ years of academic / industry experienceOrPhD in Biology with 0-2 years of academic / industry experienceDesired Skills and ExperiencesPhD in structural biology, biochemistry, or a closely related fieldDeep understanding of protein structure and function relationshipsExperience engineering antibody-based therapeutics to improve attributes such as activity, yield, immunogenicity, and developabilityExperience with high-throughput methods of cloning, production, and characterization (SDS-PAGE, SEC-MALS, MS, BLI/SPR, mass photometry) of proteinsFamiliar with generating and applying computational predictions and structural analysis in drug discovery projects (e.g. Schrodinger, MOE, and/or Rosetta)Diverse hands-on experiences including protein expression and purificationMust be highly self-motivated, detail-oriented, and well-organizedExcellent written and verbal presentation skills as evidenced by external publications and presentationsThe starting compensation for this job is a range from $128,420 - $155,600, plus incentive cash and stock opportunities (based on eligibility).The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience.Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Careers Site.Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:&nbsp;<a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Scientist - Discovery Protein Engineering

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.The Oncology Thematic Research Center at BMS is a key research and early development engine, responsible for the discovery and development of novel oncology therapeutics for patients.&nbsp; Centered at our state-of-the-art research sites in Cambridge and Seattle, scientists focus on novel targets and pathways for tumors that are refractory to current therapies.&nbsp; With a deep understanding of the causal human biology, we are able to leverage our multiple modality platforms to best match the modality to the mechanism and desired outcome.&nbsp; We are a fully integrated drug discovery through translational and early clinical development organization which exploits state-of-the-art in vitro, in vivo and ex-vivo models of Cancer biology and Immuno-oncology to identify and validate targets.&nbsp; &nbsp;We partner closely with colleagues in Translational Medicine, Informatics and Predictive Sciences and Early Clinical Development to generate biomarker and patient enrichment hypotheses to enable efficient decision making in early clinical trials.&nbsp; We are&nbsp;optimally positioned to complement the world-class translational expertise, biology and leading academic research centers in the areaPosition Summary:This position provides a chance to develop next-generation Cancer Immunology therapies that improve patient outcomes. We seek an innovative scientist with leadership potential to drive drug discovery from target nomination to IND filing within the Discovery Biology Team at Bristol Myers Squibb in Cambridge, MA. The ideal candidate will be motivated, independent, and able to work within and lead cross-functional antibody discovery teams. supporting patient and indication selection as well as the development of a biomarker plan.The candidate will guide matrixed teams through early target validation to IND filing and oversee a small group focused on in vitro biology, assay development, and compound screening studies. Proficiency in flow cytometry, mid-scale screening, T cell bioassays, molecular biology, and related methods is required.This role also involves contributing to the nomination and advancement of new Cancer Immunology targets addressing immune suppressive and other cells in the tumor microenvironment. Collaboration with bioinformaticians and translational scientists is expected for experiment design and execution.Position Responsibilities:This role offers the opportunity to drive scientific innovation and shape the strategic direction of novel immunotherapy development at BMS in a highly collaborative environment that is guided by strong science and an enduring drive to benefit patients with cancer.&nbsp;In the role as a Principal Scientist within Discovery Biology, the ideal candidate will:<ul><li>Apply comprehensive expertise in cancer immunology and antibody drug discovery to lead cross-functional discovery teams from target identification through IND submission.</li><li>Oversee and actively contribute to the activities of the biology team, ensuring effective support for in vitro experimental workflows.</li><li>Integrate internal screening data, reverse translational datasets, and insights from scientific literature to propose and develop innovative strategies in Cancer Immunology.</li><li>Collaborate with leaders from key functional areas such as in vivo pharmacology, translational biology, DMPK, informatics, and predictive science to establish priorities, evaluate risks, and advance project objectives.</li><li>Leverage advanced scientific and technical knowledge to design, validate, and conduct in vitro assays that clarify drug mechanisms of action and enhance therapeutic efficacy.</li><li>Analyze complex biological data to support informed decision-making and guide optimization of lead candidates.</li><li>Communicate scientific results and strategic recommendations clearly and effectively across the BMS organization.</li><li>Demonstrate strong communication and interpersonal abilities to promote collaboration across multidisciplinary teams.</li></ul>Experience = We are seeking a motivated scientist who combines deep immunology expertise with a passion for innovation. You thrive in a collaborative environment, enjoy solving complex biological problems, and are driven by the opportunity to make a meaningful impact on patients’ lives.Basic Qualifications: <ul><li>Bachelor’s Degree<ul><li>8+ years of academic and / or industry experience</li></ul></li></ul>Or<ul><li>Master’s Degree<ul><li>6+ years of academic and / or industry experience</li></ul></li></ul>Or<ul><li>Ph.D. or equivalent advanced degree in the Life Sciences&nbsp;<ul><li>4+ years of academic and / or industry experience</li></ul></li></ul>Preferred Qualifications<ul><li>Ph.D. or equivalent advanced degree in the Life Sciences&nbsp;<ul><li>4+ years of academic and / or industry experience</li></ul></li></ul><ul><li>Proven expertise in the discovery and development of advanced biologics that influence immune function, including bispecific antibodies, biparatopic antibodies, masked antibodies, and immune cell engagers</li><li>Extensive experience in designing, developing, and optimizing high-throughput cell-based assays for antibody screening</li><li>Direct involvement in IND-enabling studies encompassing data generation, analysis, interpretation, and documentation</li><li>Comprehensive understanding of cancer immunology with particular proficiency in T cell-based in vitro assays</li><li>Demonstrated scientific curiosity, perseverance, and a strong commitment to resolving complex biological challenges through innovative approaches</li><li>Strong leadership capabilities, with a history of mentoring or guiding scientific teams</li><li>Superior organizational skills, adept at managing and prioritizing multiple projects involving both internal and external collaborators</li><li>Established ability to analyse, interpret, and clearly communicate complex scientific data</li><li>Exceptional verbal and written communication skills, effectively tailored to both scientific and cross-functional audiences</li><li>Advanced problem-solving abilities with demonstrated application of scientific principles to address complex research questions</li></ul>The starting compensation for this job is a range from $145,320.00 - $176,100.00, plus incentive cash and stock&nbsp;opportunities (based on eligibility).&nbsp; The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual&nbsp;compensation will be decided based on demonstrated experience.&nbsp; Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS&nbsp;Career Site.&nbsp; Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical,&nbsp;pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP).&nbsp;Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental&nbsp;health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays,&nbsp;Global Shutdown days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick&nbsp; time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and&nbsp;surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like&nbsp;tuition reimbursement and a recognition program.#LI-OnsiteIf you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:&nbsp;<a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Principal Scientist, Cancer Immunology

Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise. We are dedicated to creating a diverse and welcoming environment where everyone can thrive.Why join Harvard Business School?Harvard Business School, located on a 40-acre campus in Boston, was founded in 1908 as part of Harvard University. It is among the world's most trusted sources of management education and thought leadership. For more than a century, the School's faculty has combined a passion for teaching with rigorous research conducted alongside practitioners at world-leading organizations to educate leaders who make a difference in the world. Through a dynamic ecosystem of research, learning, and entrepreneurship that includes MBA, Doctoral, Executive Education, and Online programs, as well as numerous initiatives, centers, institutes, and labs, Harvard Business School fosters bold new ideas and collaborative learning networks that shape the future of business. Job Description Job Summary:Lead comprehensive applications/web development for highly complex projects; typically work as part of a team to implement complex business solutions. Deliver strategic and expert coding; focus on overarching development strategy for a large, complex, multi-faceted application. May manage a number of projects simultaneously. 
Job Specific Responsibilities:Harvard Business School will not offer visa sponsorship for this opportunity. 
 
We are seeking a talented Generative AI Engineer to join our team. In this role, you will design, develop, and deploy state-of-the-art generative AI models, directly impacting our platform's ability to provide interactive and intelligent tools for our users. 
 
As a Senior Data Scientist specializing in Generative AI applications, you will play a pivotal role in developing innovative generative AI products that support the Harvard Business School (HBS) Foundry team and learners on our platform. This key technical role requires hands-on expertise across data science, machine learning, and AI solutions. You will manage the lifecycle of artificial intelligence algorithms and tools across a variety of domains. The Foundry Team will support with domain knowledge. 
 
AI Tool Development and Implementation<ul><li>Design and implement efficient data pipelines for data collection, cleaning, labeling, and preprocessing</li><li>Ensure quality of datasets tailored for LLM training for each product. Build data science pipelines from feature generation, data visualization and models evaluation; design the solution, build code and provide documentation with ways of working to maximize time to value, re-usability, and scalability.</li><li>Designing, developing, deploying, and implementing multi-agent AI tools that:<ul><li>Assess and provide feedback on venture-related submissions</li><li>Automatically generate pitch decks, financial projections, marketing strategies, and other materials to support entrepreneurs</li><li>Act as a counterparty to simulate important entrepreneurial interactions such as customer interviews, negotiations with an investor, etc.</li><li>Designing generative AI models using techniques like natural language processing and machine learning that can power interactive tools on HBS Foundry.</li></ul></li><li>Designing an AI-powered system that collects key factors to determine a learner’s profile, entrepreneurial progress, and venture progress, and provides customized learning pathways based on these factors.</li><li>Integrating AI tools into the HBS Foundry platform in a seamless manner so they are easy for users to access and utilize.</li><li>Collaborate on technical vision to accelerate product impact through cutting-edge LLM innovations.</li><li>Building guardrails, compliance rules, and oversight workflows into the GenAI tools and Foundry platform.</li><li>Continually improving AI tools using feedback from users to ensure they are providing valuable assistance.</li></ul>Project and Performance Management<ul><li>Monitor, debug, track, and resolve production issues.</li><li>Work with the Foundry Project Director to ensure that projects proceed on time and on budget.</li><li>Collaborate with Product Managers to ensure proper tracking of performance KPIs and prioritize improvements based on effort and impact.</li><li>Presenting prototypes and progress updates to stakeholders.</li></ul>Research and Collaboration<ul><li>Staying up to date on the latest advances in AI/ML research and identifying how new techniques could enhance the HBS Foundry platform.</li><li>Collaborating with a team of engineers, designers, and subject matter experts to deliver high-quality, helpful AI-powered experiences.</li></ul>This role is responsible for other duties as assigned.&nbsp; Qualifications Basic Qualifications:<ul><li>Minimum of seven years’ post-secondary education or relevant work experience</li><li>Advanced degree in computer science, data science, engineering, or a related field within AI/ML</li></ul>Additional/Desired Qualifications:<ul><li>3+ years of experience building (Generative) AI models and tools highly preferrable</li><li>Experience working in a similar role in a startup environment preferrable</li><li>Expertise in NLP, deep learning, and other relevant techniques</li><li>Strong programming skills in Python and frameworks like TensorFlow</li><li>Experience building advanced workflows such as retrieval augmented generation, model chaining, dynamic prompting, PEFT/SFT, etc. using Langchain and similar tools</li><li>Experience integrating AI into consumer-facing applications (front-end and back-end development for integrating AI solutions into web applications</li><li>Experience establishing model guardrails and developing bias detection and mitigation techniques for AI applications using tools (such as NeMo)</li><li>Experience with various embedding models and setting up and tuning vector databases to improve performance of semantic search and retrieval systems</li><li>Experience working with a variety of relational SQL and NoSQL databases, big data tools (such as Hadoop, Spark, Kafka), and at least one cloud provider solution (AWS highly preferrable)</li><li>Experience in using version control systems such as Git.</li><li>Experience with containerization and orchestration tools like Docker and Kubernetes.</li><li>Experience with API development and integration for AI services.</li><li>Understanding of and experience with of software engineering best practices like version control, CI/CD, and containerization</li><li>Experience establishing model guardrails and developing bias detection and mitigation techniques for AI applications</li><li>Proficiency with various prompting techniques, with a clear understanding of tradeoffs between prompting and finetuning</li><li>Experience with finetuning embedding models and tuning vector databases to improve performance of semantic search and retrieval systems</li><li>Experience operationalizing end-to-end machine learning applications.</li><li>Excellent communication and collaboration skills</li><li>Passion for using AI to solve real-world problems</li></ul> Additional Information <ul><li>Appointment End Date: June 30, 2026</li><li>Standard Hours/Schedule: 40 hours per week</li><li>Visa Sponsorship Information: Harvard University is unable to provide visa sponsorship for this position</li><li>Pre-Employment Screening: Identity, Education, Criminal</li><li>Other Information: </li></ul>This role has the possibility of being&nbsp;remote or hybrid. 
Remote&nbsp;work may be considered for individuals living at least 100-mile radius from campus and where all work will be completed within a state that Harvard is registered to do business in (CA - exempt roles only, CT, GA, IL, MA, MD, ME, NH, NJ, NY, RI, VA, VT or WA). We consider&nbsp;hybrid&nbsp;to be a combination of remote and 3 days per week onsite work at our Boston, MA based campus. Specific hours and days onsite will be determined by business needs and are subject to change with appropriate advanced notice. 
 
We may conduct candidate interviews virtually (phone and/or via Zoom) and/or in-person for this role.As part of our evaluation, candidates are required to complete a&nbsp;Take Home Assignment / Hacker Rank assessment&nbsp;after clearing Technical Recruiter Screen. This assignment will test your specific skills/knowledge areas relevant to the role 
 
A cover letter is required to be considered for this opportunity.Work Format DetailsThis is a position that is based at a Harvard campus location with some remote work options available. Additional details will be discussed during the interview process. All remote work must be performed within one of the Harvard Registered Payroll States, which currently includes Massachusetts, Connecticut, Maine, New Hampshire, Rhode Island, Vermont, Georgia, Illinois, Maryland, New Jersey, New York, Virginia, Washington, and California (CA for exempt positions only). Certain visa types and funding sources may limit work location. Individuals must meet work location sponsorship requirements prior to employment.&nbsp;
Salary Grade and RangesThis position is salary grade level 059. Please visit &nbsp;<a href="https://hr.harvard.edu/salary-ranges" target="_blank">Harvard's Salary Ranges</a>  to view the corresponding salary range and related information.&nbsp;
BenefitsHarvard offers a comprehensive benefits package that is designed to support a healthy work-life balance and your physical, mental and financial wellbeing. Because here, you are what matters. Our benefits include, but are not limited to:&nbsp;<ul><li>Generous paid time off including parental leave&nbsp;</li><li>Medical, dental, and vision health insurance coverage starting on day one&nbsp;</li><li>Retirement plans with university contributions&nbsp;</li><li>Wellbeing and mental health resources&nbsp;</li><li>Support for families and caregivers&nbsp;</li><li>Professional development opportunities including tuition assistance and reimbursement&nbsp;</li><li>Commuter benefits, discounts and campus perks&nbsp;</li></ul>Learn more about these and additional benefits on our <a href="https://hr.harvard.edu/benefits-wellbeing" target="_blank">Benefits &amp; Wellbeing Page</a>.&nbsp;
EEO/Non-Discrimination Commitment StatementHarvard University is committed to <a href="https://hr.harvard.edu/sites/g/files/omnuum6281/files/2025-04/reaffirmation_statement.pdf" target="_blank">equal opportunity</a> and <a href="https://provost.harvard.edu/files/provost/files/non-discrimination_and_anti-bullying_policies.pdf" target="_blank">non-discrimination</a>. We seek talent from all parts of society and the world, and we strive to ensure everyone at Harvard thrives. Our differences help our community advance Harvard’s academic purposes.&nbsp;Harvard has an <a href="https://hr.harvard.edu/sites/g/files/omnuum6281/files/2025-04/reaffirmation_statement.pdf" target="_blank">equal employment opportunity</a> policy that outlines our commitment to&nbsp;prohibiting discrimination on the basis of race, sex, ethnicity, color, national origin, religion, disability, or any other characteristic protected by law or identified in the university’s <a href="https://provost.harvard.edu/files/provost/files/non-discrimination_and_anti-bullying_policies.pdf" target="_blank">non-discrimination policy</a>. Harvard’s <a href="https://hr.harvard.edu/sites/g/files/omnuum6281/files/2025-04/reaffirmation_statement.pdf" target="_blank">equal employment opportunity</a> policy and <a href="https://provost.harvard.edu/files/provost/files/non-discrimination_and_anti-bullying_policies.pdf" target="_blank">non-discrimination policy</a> help all community members participate fully in work and campus life free from harassment and discrimination.&nbsp;

Senior Data Scientist, Generative AI Products

Company Description By working at Harvard University,&nbsp;you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise. We are dedicated to creating a diverse and welcoming environment where everyone can thrive.Why join the Harvard Graduate School of Education?The Harvard Graduate School of Education (HGSE) is a diverse community of learners, teachers, and employees who are passionate about changing the world through education and striving for maximum impact in the field of education.Many choose to work at the Harvard Graduate School of Education because they believe in our mission and are excited by our vision for the future. We have a reputation as a great place to work, for our excellent leadership, and we are a strong community that values diversity. For more information about HGSE, its programs, research, and faculty, please visit: <a href="http://www.gse.harvard.edu" target="_blank">www.gse.harvard.edu</a>. Job Description Job Summary:Design, plan, and implement software and data services that support and enrich research productivity and reliability.&nbsp; Develop software and data services with researchers to ensure that modern standards of reproducible research are kept. 
Position Description:HGSE is a diverse community&nbsp;of learners, teachers, and employees who are passionate about changing the world through education and striving for maximum impact in the field of education. The Senior Data Scientist at the Center for Education Policy Research (CEPR) at Harvard University leads statistical programming, collaborates with Principal Investigators to develop advanced models and analysis tools, develops data architecture and data processing pipelines, works with multiple stakeholders and develops visualizations to communicate key findings to non-technical audiences, and advises projects on state-of-the-art software and data solutions to support the research. CEPR partners with school districts, charter school networks, and state education agencies to bring high quality research methods and data analysis to bear on strategic management and policy decisions. We believe that (1) policy and management decisions directly influence the ability of schools and teachers to improve student achievement; and (2) valid and reliable data analysis significantly improves the quality of decision-making. We design our work around the theory of action that if we bring together the right people, the right data, and the right analysis, significantly better decision-making will occur, and student outcomes will be improved.&nbsp;The Senior Data Scientist reports to CEPR’s Director of Research who will identify specific projects and tasks that would benefit from the Senior Data Scientist’s expertise.&nbsp; 
&nbsp;Job-Specific Responsibilities:<ul><li>Develops advanced models and performs complex statistical programming to support the research.</li><li>Advises research projects on state-of-the-art technical solutions to analytic and data challenges.&nbsp;</li><li>Translates complex analyses for policy and practitioner audiences and develop visualizations that help people understand key findings and new insights.&nbsp;</li><li>Mentors research analysts on statistical programming and informally supervise the analyst on any tasks that the Senior Data Scientist assigns to them.</li><li>Serves as a resource to the team for computer programming and statistics. Occasionally, group training on specific tools or models.&nbsp;&nbsp;</li><li>Builds internal code design and development guides for future contributors,</li><li>Conducts quality assurance to ensure the reproducibility of analyses, documentation of methods and algorithms, and use of appropriate statistical tests.</li><li>Collaborates with Principal Investigators and Project Directors to develop research plans and statistical analyses.</li><li>Contributes to papers and reports.</li></ul>Please Note: Any candidate wishing to be considered must supply a cover letter in addition to their resume showing that they meet the required basic qualifications. Any candidate invited to an initial round of interview will be asked to submit a sample program.&nbsp; Any candidate invited to a second round of interview will be asked to complete a case.&nbsp; This is a one-year term position from the date of hire, with the possibility of extension, contingent upon work performance and continued funding to support the position.&nbsp; 
Physical Requirements: 
Working Conditions:HGSE is currently developing dynamic workplace models which will actively support a combination of on-campus and remote work (within a state in which Harvard is registered to do business) where business and operational needs allow. You and your manager will discuss the best schedule based on your role and operational need. If your role allows for remote work, please note that all remote work must be performed within a state in which Harvard is registered to do business (CA (Only Exempt), CT, GA, IL, MA, MD, ME, NH, NJ, NY, RI, VA, VT, and WA). Please also note that Harvard will withhold each applicable state’s required tax and other withholdings from your paycheck for the time you work there. 
 
The health of our workforce is a priority for Harvard University. With that in mind, we strongly encourage all employees to be up-to-date on CDC-recommended vaccines. 
 
We regret that the Harvard Graduate School of Education does not provide Visa sponsorship. Qualifications Basic Qualifications:<ul><li>Minimum of seven years’ post-secondary education or relevant work experience</li></ul> 
Additional Qualifications and Skills:Bachelor’s degree in computer science, Statistics, Data Science, Economics, Mathematics, or a related field.&nbsp;7+ years of relevant experience or post-secondary education.3+ years’ experience in advanced statistical programming using Stata or R.Additional Qualifications and Skills:&nbsp;Master’s degree preferred.5+ years experience in statistical programming preferred.3+ years experience supporting social science research projects preferred.Experience with Bayesian estimation, machine learning, natural language processing, cloud-based computing, and/or Artificial Intelligence strongly preferred.Experience with managing and analyzing large datasets, scaling processes, developing data architectures, and developing R packages preferred.Experience with version control software (such as Git), code reviews, and unit testing preferred.Ability to translate technical topics for non-technical audiences and to develop analyses and visualizations that convey key findings clearly.Demonstrated creative ability to solve challenges in novel ways using state-of-the-art statistical and data processing techniques.Experience working with K-12 or postsecondary education data a plus.&nbsp; 
Certificates and Licenses: Additional Information <ul><li>Standard Hours/Schedule:35 hours per week</li><li>Visa Sponsorship Information: Harvard University is unable to provide visa sponsorship for this position</li><li>Pre-Employment Screening:Education,Identity </li><li>Other Information:HGSE Human Resources values diversity in all forms and believes that each employee brings a set of diverse experiences and identities to the workplace that makes us stronger, encourages innovation, and enhances our collective contributions.&nbsp; We continue to develop and support a workforce that reflects the diversity of those we serve; fosters an environment that allows everyone to belong and to bring their best self to work; and creates the conditions that empower employees to contribute their full potential to advancing the work of the school.We do this by:<ul><li>Hiring and retaining staff reflecting the diversity of those we serve</li><li>Providing employees opportunities to learn, grow, and be challenged</li><li>Reviewing and ensuring fairness and equity in HR practices and policies including but not limited to hiring, promotion, and compensation</li><li>Developing strong relationships and partnerships internal and external to our community to advance diversity and inclusion</li><li>Communicating transparently and respectfully; and</li><li>Fostering an inclusive, respectful, and professional work environment</li></ul> 
About the Harvard Graduate School of Education 
 
Many choose to work at the Harvard Graduate School of Education because they believe in our mission and are excited by our vision for the future. We have a reputation as a great place to work, for our excellent leadership, and we are a strong community that values diversity. For more information about HGSE, its programs, research, and faculty, please visit: <a href="http://www.gse.harvard.edu" target="_blank">www.gse.harvard.edu</a></li></ul>Work Format DetailsThis is a position that is based at a Harvard campus location with some remote work options available. Additional details will be discussed during the interview process. All remote work must be performed within one of the Harvard Registered Payroll States, which currently includes Massachusetts, Connecticut, Maine, New Hampshire, Rhode Island, Vermont, Georgia, Illinois, Maryland, New Jersey, New York, Virginia, Washington, and California (CA for exempt positions only). Certain visa types and funding sources may limit work location. Individuals must meet work location sponsorship requirements prior to employment.&nbsp;
Salary Grade and RangesThis position is salary grade level 058. Please visit &nbsp;<a href="https://hr.harvard.edu/salary-ranges" target="_blank">Harvard's Salary Ranges</a>  to view the corresponding salary range and related information.&nbsp;
BenefitsHarvard offers a comprehensive benefits package that is designed to support a healthy work-life balance and your physical, mental and financial wellbeing. Because here, you are what matters. Our benefits include, but are not limited to:&nbsp;<ul><li>Generous paid time off including parental leave&nbsp;</li><li>Medical, dental, and vision health insurance coverage starting on day one&nbsp;</li><li>Retirement plans with university contributions&nbsp;</li><li>Wellbeing and mental health resources&nbsp;</li><li>Support for families and caregivers&nbsp;</li><li>Professional development opportunities including tuition assistance and reimbursement&nbsp;</li><li>Commuter benefits, discounts and campus perks&nbsp;</li></ul>Learn more about these and additional benefits on our <a href="https://hr.harvard.edu/benefits-wellbeing" target="_blank">Benefits &amp; Wellbeing Page</a>.&nbsp;
EEO/Non-Discrimination Commitment StatementHarvard University is committed to <a href="https://hr.harvard.edu/sites/g/files/omnuum6281/files/2025-04/reaffirmation_statement.pdf" target="_blank">equal opportunity</a> and <a href="https://provost.harvard.edu/files/provost/files/non-discrimination_and_anti-bullying_policies.pdf" target="_blank">non-discrimination</a>. We seek talent from all parts of society and the world, and we strive to ensure everyone at Harvard thrives. Our differences help our community advance Harvard’s academic purposes.&nbsp;Harvard has an <a href="https://hr.harvard.edu/sites/g/files/omnuum6281/files/2025-04/reaffirmation_statement.pdf" target="_blank">equal employment opportunity</a> policy that outlines our commitment to&nbsp;prohibiting discrimination on the basis of race, sex, ethnicity, color, national origin, religion, disability, or any other characteristic protected by law or identified in the university’s <a href="https://provost.harvard.edu/files/provost/files/non-discrimination_and_anti-bullying_policies.pdf" target="_blank">non-discrimination policy</a>. Harvard’s <a href="https://hr.harvard.edu/sites/g/files/omnuum6281/files/2025-04/reaffirmation_statement.pdf" target="_blank">equal employment opportunity</a> policy and <a href="https://provost.harvard.edu/files/provost/files/non-discrimination_and_anti-bullying_policies.pdf" target="_blank">non-discrimination policy</a> help all community members participate fully in work and campus life free from harassment and discrimination.&nbsp;

Senior Data Scientist

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.Senior Principal Scientist, Discovery Biotherapeutics, Selection TechnologiesSummaryThe Discovery Biotherapeutics team is dedicated to the discovery and advancement of novel biotherapeutic candidates, leveraging cutting-edge science and innovative technologies to drive the drug discovery pipeline. We seek to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates, and endogenous proteins in order to optimize their utility as therapeutic agents. Our team collaborates across disciplines to advance biologic programs in Oncology, Immunology, Cardiovascular, and Neuroscience with the ultimate goal of bringing new groundbreaking therapies to patients. The Selection Technologies team, a key component of Discovery Biotherapeutics, harnesses the power of in vitro display technologies such as yeast and mRNA display to discover binders against therapeutic targets of interest. We collaborate closely with computational biologists embedded directly in the Discovery Biotherapeutics organization to apply AI/ML predictions to synthetic library design, Next Generation Sequencing (NGS) analysis, and therapeutic candidate prioritization.Position ResponsibilitiesThe role of Senior Principal Scientist within Discovery Biotherapeutics, Selection Technologies involves leading a high-performing team that is responsible for conducting selections using in vitro display platforms such as yeast and mRNA display to discover binders against targets of interest. The successful candidate will be an expert in antibody discovery from in vitro methods and play a prominent role in shaping the future direction of platform development and innovation in this area. The role requires exceptional leadership and mentoring skills and the ability to collaborate across functional areas to support and potentially lead therapeutic programs.In the role as a Senior Principal Scientist within Discovery Biotherapeutics, Selection Technologies, the ideal candidate will:<ul><li>Lead a team of scientists to drive therapeutic antibody discovery efforts and foster a collaborative, goal-oriented environment.</li><li>Lead technology innovation efforts to benchmark and evolve our in vitro display platform and drive strategic decisions around synthetic library designs and platform investments.</li><li>Collaborate closely with computational and data science colleagues to leverage AI/ML and other computational methods applied to biotherapeutic discovery and to generate new ways of analyzing data.</li><li>Drive binder discovery and selection strategy across therapeutic programs.</li><li>Leverage cross-functional collaboration skills to lead therapeutic projects and/or technology initiatives.</li></ul>Experience - Basic Qualifications<ul><li>Bachelor’s Degree<ul><li>10+ years of academic and/or industry experience</li></ul></li></ul>Or<ul><li>Master’s Degree<ul><li>8+ years of academic and/or industry experience</li></ul></li></ul>Or<ul><li>Ph.D. or equivalent advanced degree in the Life Sciences<ul><li>6+ years of academic and/or industry experience</li><li>2+ years of leadership experience</li></ul></li></ul>Experience - Preferred Qualifications<ul><li>Ph.D. or equivalent with 6+ years of industry experience and 4+ years of leadership experience.</li><li>Technical expertise in performing and supervising in vitro display experiments, including yeast, mRNA, phage, and/or mammalian display platforms.</li><li>Experience implementing and/or building in vitro antibody discovery platforms, such as designing synthetic antibody libraries or developing new in vitro display systems.</li><li>Experience analyzing antibody variable region sequences, including data from Next Generation Sequencing (NGS).</li><li>Experience leading therapeutic projects or technology initiatives that involve cross-functional matrix teams.</li><li>Exceptional interpersonal and communication skills, with the capability of leading and developing a high-performing experimental team.</li><li>Demonstrated ability to attract and retain top talent, and a commitment to talent development and diversification.</li><li>Proven track record of scientific innovation, peer-reviewed publications, and IP generation is a plus.</li><li>Experience working with generative binder methods and structure-enabled design is a plus.</li><li>Experience with multiple antibody formats, including Fab, scFv, and single domain/VHH is a plus.</li><li>Proven leadership and experience managing matrix research teams and advancing biologics binder generation or therapeutic programs is a plus.</li></ul>The starting compensation for this job is a range from $184,720 - $223,800, plus incentive cash and stock opportunities (based on eligibility).The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience.Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Careers Site.Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:&nbsp;<a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Senior Principal Scientist, Discovery Biotherapeutics, Selection Technologies

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.JOB DESCRIPTIONWe are seeking an experienced and collaborative Principal AI Scientist to lead the design and deployment of multi-objective optimization and predictive modeling solutions for biologics discovery and design. This role is an integral part of our Computational Design and Predictive Modeling team, which sits at the interface of cutting-edge AI and therapeutic innovation.You will use high-dimensional assay data and antibody repertoires to develop innovative, accurate, and scalable computational solutions that guide molecular design and optimization efforts. You will also pioneer the integration of state-of-the-art AI techniques into real-world biologics pipelines, working closely with wet-lab scientists, bioinformaticians, protein engineers, and drug discovery program teams.RESPONSIBILITIES<ul><li>Design, develop, and deploy multi-objective optimization frameworks that guide antibody candidate selection and optimization.</li></ul><ul><li>Build and maintainpredictive models that estimate drug-like attributes (e.g., binding affinity, expression, developability, immunogenicity, viscosity) from high-throughput assay and sequence data.</li></ul><ul><li>Collaborate with project teams to formulate optimization goals and define interpretable, model-informed design strategies.</li></ul><ul><li>Lead the application of cutting-edge ML methods, including Bayesian optimization, active learning, transformers, and diffusion models, to antibody design problems.</li></ul><ul><li>Architect pipelines that integrate real-time experimental feedback into active learning or design-make-test-learn loops.</li></ul><ul><li>Translate high-impact innovations into robust tools and workflows deployable across therapeutic programs.</li></ul><ul><li>Contribute to scientific strategy, internal capability building, and external visibility through reports, seminars, meetings, and collaborations.</li></ul>QUALIFICATIONS<ul><li>Ph.D. in computer science, machine learning, statistics, computational biology, or related fields with 6+ years of relevant experience in industry or academia.</li></ul><ul><li>Demonstrated expertise in multi-objective optimization, Bayesian methods, reinforcement learning, or active learning applied to molecular design or related scientific domains.</li></ul><ul><li>Strong background in deep learning, including transformer architectures, variational autoencoders, diffusion models, or GNNs.</li></ul><ul><li>Fluency in Python and modern ML libraries (e.g., PyTorch, TensorFlow, JAX), with excellent software engineering practices (Git, CI/CD, containerization, and reproducible research standards).</li></ul><ul><li>Experience working with large-scale biological datasets, including sequences, assay measurements, and structural data.</li></ul><ul><li>Track record of innovation and technical leadership in complex, multidisciplinary projects.</li></ul><ul><li>Strong written and oral communication skills, with an ability to explain complex models to cross-functional teams and translate business needs into ML solutions.</li></ul><ul><li>Knowledge in protein biochemistry or antibody engineering is a strong plus.</li></ul><ul><li>Familiarity with high-performance computing and cloud-based infrastructure is desirable.</li></ul>If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:&nbsp;<a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Principal Scientist (AI/ML) – Predictive modeling, design and optimization for therapeutic antibodies

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.Bristol-Myers Squibb is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health.&nbsp; We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries - and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.BMS R&amp;D is at a critical and exciting phase of development. As it expands and integrates its portfolio including small molecules, biologics and cell therapies, there is an opportunity for a dynamic and resourceful individual to lead a team of innovative laboratory scientists that are addressing scientific questions in support of programs managed by the Translational Medicine group at our site in Summit, NJ.&nbsp;Translational Development at BMS&nbsp;Translational Development is part of the Global Research organization in BMS and leads late stage clinical, pharmacological and translational research and development activities for the pipeline and supports late stage portfolio for regulatory, translational development and life cycle management. Translational Development drives strategy across core therapeutic areas at BMS including hematology, oncology, immunology, cardiovascular and neuroscience. This group integrates laboratory science, clinical trial/biomarkers and asset development as well as disease research to maximize the potential of BMS current and future therapeutics.&nbsp;therapeutics.&nbsp;SummaryReporting to Director/Associate Director, Translational Development, the incumbent will be part of the translational group based in Cambridge, MA and will manage the scientific and preclinical laboratory component of multiple late stage hematology programs (phase 2 and beyond). Key responsibilities of this role are to lead from the bench for the preclinical support of asset programs through mechanism of action-based studies, differentiation from standard of care molecules, combination rationale and resistance mechanisms.Responsibilities<ul><li>Supports preclinical/laboratory component of late stage BMS compounds to support annual goals and objectives for the Heme Translational Medicine group (for internal /external, collaborations, compound specific plans etc).&nbsp;</li><li>Responsible for delivering data in support of translational strategies including biomarkers, patient selection hypotheses, dose and schedule, combination strategies, resistance mechanisms and differentiation</li><li>Interfaces with other research scientists within and outside of TD to ensure seamless flow of information for assets which are entering the remit of translational development</li><li>May contribute to a portfolio of preclinical collaborations across the pipeline compounds for clinical assets&nbsp;</li><li>Communicates regularly and prepares and makes presentations within the department</li></ul> Qualifications<ul><li>PhD with at least 2 years of relevant work experience. Experience including drug development in an industry setting, especially hematology indications is a plus.</li><li>Strong publication record and track record in academic or industry setting, leading innovative efforts within the laboratory setting to achieve defined goals and support clinical development</li><li>Excellent communication, managerial and scientific qualities are expected</li><li>Competence in analysis and solving of problems, and the ability to prioritize and make tradeoffs to achieve goals.</li></ul>Technical Skills<ul><li>In depth understanding of cancer biology, immunology and/or neuroscience</li><li>Some understanding of drug development process in an industry setting</li><li>Some understanding of late-stage drug and translational development process</li><li>Ability to work with disease teams/experts to develop preclinical strategies to support clinical development and life cycle management</li><li>Strong verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications</li></ul>Other Attributes<ul><li>A problem solver</li><li>Identifies issues early and proposes innovative solutions.</li><li>Communicates within the TD team</li></ul>If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:&nbsp;<a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

9 Natural and Environmental Sciences Jobs in Massachusetts