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Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.The Pharmaceutical Candidate Optimization organization at Bristol Myers Squibb is a dynamic, multi-disciplinary department that works to discover and optimize new drug candidates.&nbsp; We&nbsp;work across all therapeutic areas and all modalities (small molecules, biotherapeutics, gene and cell therapies and other novel modalities),and engage with all other R&amp;D functions to advance new assets in the BMS portfolio. &nbsp;Our integrated, cross-functional teams apply deep expertise in drug metabolism, pharmacokinetics (DMPK), toxicology, pharmaceutics, and bioanalysis to identify and solve issues, discover high quality drug candidates, and enable their clinical development. Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.Position Summary:We are seeking an innovative scientist to join the Discovery Toxicology laboratory at BMS San Diego. The Discovery Toxicology team supports the early-stage discovery of pharmaceuticals, including early risk assessment, mechanistic investigation, and risk mitigation from initial target identification through to development candidate nomination. The scientist will serve as an integral member of the Discovery Toxicology team and conduct experiments to support the progression of assets across modalities (e.g., small molecule, targeted protein degraders, antibody-drug conjugates, oligonucleotides, peptides, etc.) within the discovery portfolio. The successful candidate will be expected to explore and evaluate novel assays and laboratory techniques to expand internal capabilities and contribute to the advancement of toxicology research. A key area of research will include the development, characterization, and qualification of complex in vitro models for toxicology-related contexts of use including but not limited to organoids, spheroids, and microphysiological systems such as tissue chips. Advanced experience in primary cell culture and molecular biology is essential, and education/background in toxicology, cell biology, biomedical engineering, or a related field is required.&nbsp;Key Responsibilities:<ul><li>Design, execute, troubleshoot, and interpret in vitro cell culture and molecular biology experiments</li><li>Develop and evaluate primary cell-based and/or iPSC-based complex in vitro models</li><li>Apply analytical techniques such as ELISA, PCR, CRISPR, biochemical assays, immunofluorescence, Jess, etc., for the functional evaluation of in vitro models</li><li>Author internal reports and manuscripts associated with exploratory/investigative activities in scientific journals and present research internally and at external conferences</li><li>Develop and maintain clear assay protocols and data documentation to facilitate method sharing among scientists in Discovery Toxicology</li><li>Learn to conduct analytical assays that can support broad-based mechanistic toxicology investigations</li><li>Work collaboratively with functional experts across the organization to successfully execute projects</li></ul>Basic Qualifications:<ul><li>Master’s with 3+ years relevant experience in industry or academic equivalent or PhD in Toxicology or other relevant discipline (e.g., Pharmacology, Biomedical Engineering, Immunology, Biology, etc.) and a general understanding of drug discovery and development is required</li></ul>Preferred Qualifications:<ul><li>Proficient mammalian cell culture skills are required with experience in primary cell culture</li><li>Experience working with complex in vitro models such as organs-on-chip, 3D tissues, spheroids, organoids, etc. is desired but not essential</li><li>Expertise in molecular biology techniques and assay development (e.g., ELISA, western blotting, multiplexed protein analysis, PCR, gene editing, etc.) is required</li><li>Ability to design, execute, troubleshoot, and interpret in vitro experiments and develop protocols to facilitate method sharing among scientists in Discovery Toxicology</li><li>Ability to work in a collaborative team environment</li><li>Advanced written and verbal communication skills are a must</li></ul>#LI-OnsiteIf you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Compensation Overview:San Diego - CA - US: $118,450 - $143,531&amp;#xa;The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.&nbsp; Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit <a href="https://careers.bms.com/life-at-bms/" target="_blank">https://careers.bms.com/life-at-bms/</a>. Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.Supporting People with DisabilitiesBMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.Candidate RightsBMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:&nbsp;<a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Data ProtectionWe will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at <a href="https://careers.bms.com/fraud-protection" target="_blank">https://careers.bms.com/fraud-protection</a>.Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Bristol Myers Squibb

Scientist, Discovery Toxicology

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.The Protein Homeostasis Thematic Research Center (TRC) at BMS is a fundamental Oncology research engine delivering oncology and hematology therapeutics to patients. The TRC has a major focus on exploiting BMS’ expertise in protein degradation to discover and develop therapies aimed at tumor intrinsic vulnerabilities and mechanisms of resistance to existing cancer therapeutics. This focus on protein degradation allows us to attack protein classes that were previously deemed undruggable.The Pharmacology group within the Protein Homeostasis TRC at BMS San Diego provides in vivo pharmacology support to discovery teams focused on developing small molecules and biologics for oncology and immune-oncology. As an integral part of discovery programs, the group supports lead identification through in vivo model screening and mechanism-of-action studies, develops and validates animal disease models, identifies pathway biomarkers, and establishes clinically relevant endpoints to assess efficacy. Collaboration with DMPK, Exploratory Toxicology, and Translational Development is central to our work, and we contribute preclinical data to inform clinical development plans.Position Summary: We are seeking a motivated Associate Scientist with broad experience in pharmacology and drug discovery for both small and large molecules. The successful candidate will work collaboratively in a multidisciplinary environment, taking responsibility for experiment design, planning, and execution. Key duties include interpreting and presenting in vivo data, conducting sample and endpoint analyses (ELISA, Western blot, Jess, qPCR, IHC), and preparing protocols and reports. The role requires independent work, technical expertise, and contributions to project decisions. Strong communication, self-motivation, innovation, flexibility, and teamwork are essential.Position Responsibilities:In the role as an Associate Scientist within Pharmacology, the ideal candidate will be responsible for the following:<ul><li>Develop disease models for oncology and immune-oncology</li><li>Independently design and execute in vivo efficacy and PK/PD experiments to identify drug candidates</li><li>Analyze and interpret data accurately, reporting findings to supervisors and colleagues</li><li>Troubleshoot routine issues and recommend solutions</li><li>Evaluate endpoints from in vivo studies using Western blots, mesoscale, qPCR, etc.</li><li>Write precise protocols and technical reports</li><li>Present data to multidisciplinary discovery teams</li><li>Collaborate with cross-functional team members</li></ul>Basic Qualifications: <ul><li>Bachelor’s Degree<ul><li>2+ years of academic and / or industry experience</li></ul></li></ul>Preferred Qualifications: <ul><li>Bachelor's Degree and 2+ years of academic and / or industry experience with oncology models</li><li>Experience in mammalian cell culture</li><li>Experience in the development of syngeneic and xenograft cancer models</li><li>Proficient in animal handling, dosing (PO, IP, IV, and SC), tumor cell inoculation, data collection and analysis</li><li>Hands-on experience in small animal surgeries, necropsy and tissue and blood collection</li><li>Hands-on experience in evaluating small molecules in animal models</li><li>Experience with small animal imaging modalities (e.g., Xenogen, ultrasound etc.) is a plus.</li><li>Skilled in Western blots, ELISA, MesoScale, IHC, flow cytometry, RNA/DNA extraction, and PCR</li><li>Proficient in Excel, Word, PowerPoint, FlowJo, GraphPad Prism, and Studylog</li><li>Excellent interpersonal, communication, presentation, collaboration, and organizational skills</li><li>Detail-oriented, focused, and able to deliver high-quality data efficiently</li></ul>LI-OnsiteIf you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Compensation Overview:San Diego - CA - US: $93,230 - $112,970&amp;#xa;The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.&nbsp; Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit <a href="https://careers.bms.com/life-at-bms/" target="_blank">https://careers.bms.com/life-at-bms/</a>. Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.Supporting People with DisabilitiesBMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.Candidate RightsBMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:&nbsp;<a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Data ProtectionWe will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at <a href="https://careers.bms.com/fraud-protection" target="_blank">https://careers.bms.com/fraud-protection</a>.Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Associate Scientist - In Vivo Pharmacology

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.SummaryThe Associate Director of Clinical Science plays a supportive role in clinical development of RazyeBio radiopharmaceuticals for oncology indications. Working in collaboration with clinical development, the position is responsible for various aspects of ongoing clinical trial program-related activities within the relevant therapeutic area. These activities include, but are not limited to, collaboration on functional area activities during program implementation, clinical study start-up/execution/close out, data analysis/reporting, and potentially support of NDA/MAA filings.Job Responsibilities<ul><li>Essential duties and responsibilities include the following.&nbsp; Other duties may be assigned.</li><li>Acquires and utilizes knowledge of clinical trial design to develop or oversee development of specific study concept synopses and protocols.</li><li>Participates in protocol review discussions concerning scientific and procedural aspects of study design.</li><li>In collaboration with Medical Writing and Clinical Operations, prepares study protocols, amendments, specific sections of study manuals and Investigator meeting materials, and other documents as needed with appropriate guidance and supervision.</li><li>Contributes to the design, development, and review of CRFs, Data Management Manuals, and Data Analysis Plans.</li><li>Reviews ongoing clinical data.</li><li>Organizes and oversees Data Review Committee meetings, including preparation of slides and other review and meeting materials.</li><li>With MD supervision, addresses questions regarding scientific and related procedural issues from Investigators.</li><li>Contributes to the preparation and/or review of data listings, summary tables, study results, manuscripts, and scientific presentations.</li><li>Assists in the preparation/review of INDs, regulatory documents, IND annual report/DSURs, Investigator Brochures, and NDAs/MAAs.</li><li>Supports priorities within functional area. </li><li>Anticipates moderately complex obstacles within a clinical study and, with guidance, implements solutions. </li><li>May be asked to coordinate teams and provide direction. </li><li>May lead two or more specific components of departmental strategic initiatives. </li><li>Able to enter a new therapeutic area and summarize scientific information that is available in published literature to integrate into new study development. </li><li>Excellent verbal and written communication skills and interpersonal skills are required to maintain working relationship with team members to ensure scientific integrity of clinical studies. </li><li>May be sought out for advice by others within the company to help make better decisions and resolve moderately complex problems. </li><li>20% of travel required</li></ul>Education and Experience<ul><li>PharmD or PhD preferred</li><li>6+ years of relevant drug development experience with a MS. </li><li>8+ years of relevant drug development experience with a BS degree in Biological Sciences, health care, or a related field. </li><li>Minimum of 5 years’ experience in clinical research or clinical pharmacology in a biotech/pharmaceutical company, contract research organization. </li></ul>Skills and Qualifications<ul><li>Demonstrated ability to be a fast learner. </li><li>Demonstrated ability to be flexible and adaptable to change, to move between projects easily and provide support/expertise where needed. </li><li>Experienced with Microsoft Office (Excel, PowerPoint, etc.) as well as job-related programs such as SpotFire.</li><li>Knowledge of FDA, EMA and ICH regulations and guidelines a must.</li><li>Ability to effectively collaborate cross-functionally, across all levels of the organization.</li></ul>#RayzebioIf you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Compensation Overview:Princeton - NJ - US: $173,217 - $209,899 &amp;#xa;San Diego - RayzeBio - CA: $190,539 - $230,888&amp;#xa;The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.&nbsp; Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit <a href="https://careers.bms.com/life-at-bms/" target="_blank">https://careers.bms.com/life-at-bms/</a>. Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:&nbsp;<a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Associate Director, Clinical Science

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.RayzeBio, a Bristol Myers Squibb company, is a dynamic biotechnology company headquartered in San Diego, CA. The company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio is developing innovative drugs against targets of solid tumors. Led by a successful and experienced entrepreneurial team, RayzeBio aims to be the global leader in radiopharmaceuticals.This position will be responsible for conducting research, experiments, and analysis in the field of radiochemistry. This role involves radiolabeling of diagnostic and therapeutic radioisotopes of peptides, small molecules, and/or antibodies as well as quality testing for in vitro and in vivo work. The Scientist will work in laboratory settings, collaborating with interdisciplinary teams to advance scientific knowledge and contribute to the advancement of all RayzeBio’s internal programs.Job Responsibilities<ul><li>Essential duties and responsibilities include the following.&nbsp; Other duties may be assigned.</li><li>Develop methods and conduct experiments to radiolabel peptides, small molecules and/or antibodies using various isotopes </li><li>Develop and execute methods for the characterization of radiolabeled compounds, using techniques such as radio-HPLC and radio-TLC chromatography to analyze purity and stability of the radiolabeled compounds</li><li>Develop methods and recipes and perform regular syntheses of radiotracers on automated synthesis devices</li><li>Develop methods and conduct in vitro assays (e.g. plasma stability and metabolite analysis) with radiolabeled compounds </li><li>Collaborate with interdisciplinary teams of discovery scientists and researchers as well as external partners (such as CROs) to address complex scientific questions and pursue collaborative research projects</li><li>Analyze experimental data, interpret results, and draw conclusions based on scientific principles. Document findings in technical reports and presentations for internal review and meetings</li><li>Present at meetings to provide timely input to progress the programs forward</li><li>Maintain a clean and safe working environment</li></ul>Education and Experience<ul><li>A Ph.D or Master’s degree in radiochemistry, chemistry, nuclear chemistry or related field</li><li>A minimum of 3 years of experience in radiochemistry field</li><li>Demonstrated experience in radiochemistry synthesis, purification, and quality control instruments such as HPLC, TLC and gamma counter</li><li>Proper radiation safety practices during radiosynthesis, radioanalytical chemistry operations, and within the lab areas at all times.</li><li>Ability to work both collaboratively and independently in a fast-paced and cross-functional environment with evolving priorities</li></ul>Skills<ul><li>Hands on experience working with diagnostic radioisotopes (F-18, Ga-68, Cu-64, Zr-89) and therapeutic radioisotopes (Lu-177, Ac-225, Tb-161, Pb-212)</li><li>Experience working with automated synthesis modules</li><li>Highly motivated and organized professional with the ability to work both with a team and independently</li><li>Multi-disciplined scientist with ability to troubleshoot</li><li>Excellent professional ethics, integrity, and ability to maintain confidential information</li></ul>Physical DemandsWhile performing the duties of this&nbsp;job, the employee is regularly required to sit, reach with hands and arms, and talk or hear. The employee must occasionally lift and/or move up to 60 pounds. Specific vision abilities required by this&nbsp;job&nbsp;include&nbsp;close vision and distance vision.&nbsp;This is a position that requires working in a laboratory environment, protective clothing, gloves, and safety glasses are required while working in a laboratory environment with radioactive materials.Work&nbsp;EnvironmentThe noise level in the&nbsp;work&nbsp;environment is usually moderate.#RayzeBioIf you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Compensation Overview:San Diego - RayzeBio - CA: $128,812 - $156,089&amp;#xa;The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.&nbsp; Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit <a href="https://careers.bms.com/life-at-bms/" target="_blank">https://careers.bms.com/life-at-bms/</a>. Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:&nbsp;<a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Scientist, Radiochemistry

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.RayzeBio, a Bristol Myers Squibb company, is a dynamic biotechnology company headquartered in San Diego, CA. The company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio is developing innovative drugs against targets of solid tumors. Led by a successful and experienced entrepreneurial team, RayzeBio aims to be the global leader in radiopharmaceuticals.The Sr. Scientist, Radiopharmaceutical Development is a leading contributor in the design, development, and advancement of RayzeBio’s radiopharmaceutical programs. This senior role is responsible for driving innovative research in novel isotope and chelator development, translating cutting-edge scientific discoveries into robust clinical drug products. The Sr. Scientist will lead CMC radiopharmaceutical process development, oversee IND-enabling activities, and play a pivotal role in clinical manufacturing. This position demands expertise in radiochemical synthesis, analytical techniques, and radiopharmaceutical formulation, as well as a proven ability to manage complex projects and mentor junior staff.Job ResponsibilitiesEssential duties and responsibilities include the following. Other duties may be assigned.<ul><li>Process Development &amp; Scale-Up:&nbsp;Drive CMC process development and optimization for clinical drug products, including formulation lock and robust process definition, ensuring scalability and compliance with regulatory standards.</li><li>Technology Transfer:&nbsp;Lead the transfer of advanced radiopharmaceutical processes and technologies to internal and external manufacturing sites, including the Indianapolis facility and CDMO partners.</li><li>Laboratory Oversight:&nbsp;Oversee the development, operation, and maintenance of radiochemistry laboratory infrastructure, ensuring readiness for translational activities from preclinical through clinical phases.</li><li>Collaboration:&nbsp;Foster collaborative relationships with discovery scientists, external academic partners, and CDMOs to address complex scientific questions and pursue joint research efforts.</li><li>Lead Research Initiatives:&nbsp;Independently design and execute advanced radiochemistry and radiolabeling experiments, with a special focus on novel radioisotope and chelator development to enable new classes of radiopharmaceuticals.</li><li>Technical Leadership:&nbsp;Serve as a subject matter expert in radiopharmaceutical production processes, quality control, and advanced analytical methodologies. Provide scientific leadership across multidisciplinary teams.</li><li>Innovation in Isotope and Chelator Chemistry:&nbsp;Direct research into the identification, synthesis, and characterization of novel isotopes and chelators to enhance therapeutic and diagnostic radiopharmaceutical properties.</li><li>Safety &amp; Compliance:&nbsp;Ensure strict adherence to radiation safety protocols, federal and state regulations, and internal guidelines for handling radioactive materials; promote a culture of safety-first and regulatory compliance.</li><li>Data Analysis &amp; Reporting:&nbsp;Interpret complex experimental data, draw scientifically rigorous conclusions, and communicate findings in technical reports, regulatory documentation, and presentations for internal and external stakeholders.</li><li>Project Management &amp; Mentorship:&nbsp;Manage and prioritize research projects, oversee third-party vendors, and mentor junior scientists and associates.</li><li>Documentation:&nbsp;Draft and review CMC sections for regulatory submissions, SOPs, and comprehensive development reports.</li><li>Travel:&nbsp;Less than 10% travel required, including external research sites and manufacturing facilities.</li></ul>Education and Experience<ul><li>BSc +7 years, MSc + 5 years or PhD +3 years in Chemistry, Radiochemistry, Pharmaceutical Sciences, or related field with relevant industry experience, including significant work with radioactive materials, novel isotopes, and chelator chemistry.</li><li>Demonstrated expertise in radiochemical synthesis, purification, formulation, and analytical techniques.</li><li>Proven track record of innovation in radiopharmaceutical development, including novel isotope and chelator research.</li><li>Deep familiarity with federal and state regulatory requirements and safety protocols for radioactive materials.</li></ul>Skills and Qualifications<ul><li>Advanced experience developing stable radiopharmaceutical formulations with targeted attributes such as extended shelf-life, radiochemical purity, and enhanced bio-distribution.</li><li>Hands-on expertise with commercial and custom radiopharmaceutical manufacturing and analytical equipment systems, including automation platforms, radioHPLC, radioTLC, gamma counters, dose calibrators, hot cell manipulators, and advanced gamma spectroscopy.</li><li>Extensive experience with a broad spectrum of radioactive materials for both diagnostic and therapeutic applications.</li><li>Strong professional ethics, integrity, and ability to maintain confidential information.</li><li>Outstanding written and verbal communication skills, with the ability to influence and communicate effectively across all levels, including executive leadership.</li><li>Proactive, innovative thinker who thrives in a fast-paced, multi-disciplinary industrial environment.</li><li>Demonstrated ability to manage complex research projects and mentor junior staff.</li></ul>Physical DemandsWhile performing duties, the employee is regularly required to sit, reach with hands and arms, and talk or hear. Occasional lifting and/or moving up to 30 pounds may be required. Specific vision abilities include close and distance vision. Lab work requires use of protective clothing, gloves, and safety glasses.Laboratory environment with moderate noise levels; strict adherence to safety protocols for working with radioactive materials is required.#RayzeBioIf you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Compensation Overview:San Diego - RayzeBio - CA: $131,028 - $158,775&amp;#xa;The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.&nbsp; Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit <a href="https://careers.bms.com/life-at-bms/" target="_blank">https://careers.bms.com/life-at-bms/</a>. Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:&nbsp;<a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

5 Natural and Environmental Sciences Jobs in San Diego, CA, USA