Sr. Scientist, Radiopharmaceutical Development

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

RayzeBio, a Bristol Myers Squibb company, is a dynamic biotechnology company headquartered in San Diego, CA. The company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio is developing innovative drugs against targets of solid tumors. Led by a successful and experienced entrepreneurial team, RayzeBio aims to be the global leader in radiopharmaceuticals.

The Sr. Scientist, Radiopharmaceutical Development is a leading contributor in the design, development, and advancement of RayzeBio’s radiopharmaceutical programs. This senior role is responsible for driving innovative research in novel isotope and chelator development, translating cutting-edge scientific discoveries into robust clinical drug products. The Sr. Scientist will lead CMC radiopharmaceutical process development, oversee IND-enabling activities, and play a pivotal role in clinical manufacturing. This position demands expertise in radiochemical synthesis, analytical techniques, and radiopharmaceutical formulation, as well as a proven ability to manage complex projects and mentor junior staff.

Job Responsibilities

Essential duties and responsibilities include the following. Other duties may be assigned.

• Process Development & Scale-Up: Drive CMC process development and optimization for clinical drug products, including formulation lock and robust process definition, ensuring scalability and compliance with regulatory standards.
• Technology Transfer: Lead the transfer of advanced radiopharmaceutical processes and technologies to internal and external manufacturing sites, including the Indianapolis facility and CDMO partners.
• Laboratory Oversight: Oversee the development, operation, and maintenance of radiochemistry laboratory infrastructure, ensuring readiness for translational activities from preclinical through clinical phases.
• Collaboration: Foster collaborative relationships with discovery scientists, external academic partners, and CDMOs to address complex scientific questions and pursue joint research efforts.
• Lead Research Initiatives: Independently design and execute advanced radiochemistry and radiolabeling experiments, with a special focus on novel radioisotope and chelator development to enable new classes of radiopharmaceuticals.
• Technical Leadership: Serve as a subject matter expert in radiopharmaceutical production processes, quality control, and advanced analytical methodologies. Provide scientific leadership across multidisciplinary teams.
• Innovation in Isotope and Chelator Chemistry: Direct research into the identification, synthesis, and characterization of novel isotopes and chelators to enhance therapeutic and diagnostic radiopharmaceutical properties.
• Safety & Compliance: Ensure strict adherence to radiation safety protocols, federal and state regulations, and internal guidelines for handling radioactive materials; promote a culture of safety-first and regulatory compliance.
• Data Analysis & Reporting: Interpret complex experimental data, draw scientifically rigorous conclusions, and communicate findings in technical reports, regulatory documentation, and presentations for internal and external stakeholders.
• Project Management & Mentorship: Manage and prioritize research projects, oversee third-party vendors, and mentor junior scientists and associates.
• Documentation: Draft and review CMC sections for regulatory submissions, SOPs, and comprehensive development reports.
• Travel: Less than 10% travel required, including external research sites and manufacturing facilities.

Education and Experience

• BSc +7 years, MSc + 5 years or PhD +3 years in Chemistry, Radiochemistry, Pharmaceutical Sciences, or related field with relevant industry experience, including significant work with radioactive materials, novel isotopes, and chelator chemistry.
• Demonstrated expertise in radiochemical synthesis, purification, formulation, and analytical techniques.
• Proven track record of innovation in radiopharmaceutical development, including novel isotope and chelator research.
• Deep familiarity with federal and state regulatory requirements and safety protocols for radioactive materials.

Skills and Qualifications

• Advanced experience developing stable radiopharmaceutical formulations with targeted attributes such as extended shelf-life, radiochemical purity, and enhanced bio-distribution.
• Hands-on expertise with commercial and custom radiopharmaceutical manufacturing and analytical equipment systems, including automation platforms, radioHPLC, radioTLC, gamma counters, dose calibrators, hot cell manipulators, and advanced gamma spectroscopy.
• Extensive experience with a broad spectrum of radioactive materials for both diagnostic and therapeutic applications.
• Strong professional ethics, integrity, and ability to maintain confidential information.
• Outstanding written and verbal communication skills, with the ability to influence and communicate effectively across all levels, including executive leadership.
• Proactive, innovative thinker who thrives in a fast-paced, multi-disciplinary industrial environment.
• Demonstrated ability to manage complex research projects and mentor junior staff.

Physical Demands

While performing duties, the employee is regularly required to sit, reach with hands and arms, and talk or hear. Occasional lifting and/or moving up to 30 pounds may be required. Specific vision abilities include close and distance vision. Lab work requires use of protective clothing, gloves, and safety glasses.

Laboratory environment with moderate noise levels; strict adherence to safety protocols for working with radioactive materials is required.

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If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview:

San Diego - RayzeBio - CA: $131,028 - $158,775


The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

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